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Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Updated: Jul 11, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

MRI in multiple sclerosis: what's inside the toolbox?

Mohit Neema¹, James Stankiewicz, Ashish Arora

¹Department of Neurology, Center for Neurological Imaging, Partners MS Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics

|October 9, 2007

Summary

This summary is machine-generated.

Magnetic resonance imaging (MRI) is vital for multiple sclerosis (MS) diagnosis and treatment. Advanced MRI techniques offer deeper insights into MS pathology and clinical progression than conventional methods.

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Last Updated: Jul 11, 2026

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Area of Science:

Neuroimaging
Neurology
Radiology

Background:

Magnetic resonance imaging (MRI) is crucial for diagnosing and managing multiple sclerosis (MS).
Conventional MRI metrics are limited in fully characterizing MS pathology and predicting clinical progression.

Purpose of the Study:

To provide an overview of conventional and advanced MRI techniques for assessing MS.
To review recent data on the role of MRI in MS assessment, focusing on pathological and clinical correlations.

Main Methods:

Review of conventional MRI techniques.
Overview of advanced quantitative MRI measures including magnetization transfer, spectroscopy, diffusion imaging, and relaxometry.
Focus on studies correlating MRI findings with MS pathology and clinical status.

Main Results:

Conventional MRI provides macroscopic insights but struggles to capture diffuse pathology.
Advanced quantitative MRI techniques demonstrate higher specificity and sensitivity for detecting diffuse white and gray matter damage in MS.
Advanced MRI metrics show potential to bridge the gap between clinical findings and conventional MRI observations.

Conclusions:

Advanced MRI techniques are essential for a comprehensive understanding of multiple sclerosis.
These methods improve the assessment of underlying pathology and may enhance prediction of clinical progression in MS.
Further research correlating advanced MRI measures with clinical outcomes is warranted.