Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diffusion tensor imaging in patients with essential tremor.

D H Shin1, B S Han, H S Kim

  • 1Department of Neurology, Ajou University College of Medicine, Suwon, South Korea.

AJNR. American Journal of Neuroradiology
|October 9, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Isolated Acute Appendicitis Caused by Aspergillus in a Patient Who Underwent Lung Transplantation: A Case Report.

Transplantation proceedings·2018
Same author

Dietary total, animal, vegetable calcium and type 2 diabetes incidence among Korean adults: The Korean Multi-Rural Communities Cohort (MRCohort).

Nutrition, metabolism, and cardiovascular diseases : NMCD·2017
Same author

Regarding "Perfusion MR Imaging Using a 3D Pulsed Continuous Arterial Spin-Labeling Method for Acute Cerebral Infarction Classified as Branch Atheromatous Disease Involving the Lenticulostriate Artery Territory".

AJNR. American journal of neuroradiology·2017
Same author

A Case of Ectopic Paragonimiasis in a 17th Century Korean Mummy.

The Journal of parasitology·2017
Same author

Radiation shielding analysis of a special linear accelerator for electron beam and X-ray.

Journal of X-ray science and technology·2017
Same author

Measurement of levels of fractional exhaled nitric oxide in patients with pulmonary tuberculosis.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2016

Essential tremor (ET) may be a progressive neurologic disorder. Diffusion tensor imaging reveals widespread white matter (WM) changes in patients with ET, suggesting structural abnormalities beyond the cerebellum.

Area of Science:

  • Neuroimaging
  • Neurology
  • Diffusion Tensor Imaging

Background:

  • Essential tremor (ET) was traditionally considered benign.
  • Emerging evidence suggests ET is a progressive neurologic disorder.
  • Cerebellar degeneration and white matter (WM) wallerian degeneration are implicated in ET.

Purpose of the Study:

  • To investigate white matter (WM) anisotropy changes in essential tremor (ET).
  • To explore structural alterations in patients with ET using diffusion tensor imaging (DTI).

Main Methods:

  • Diffusion tensor imaging (DTI) data acquired at 1.5T.
  • 10 patients with ET compared to 8 healthy controls.
  • Voxel-by-voxel analysis using statistical parametric mapping.

Related Experiment Videos

Main Results:

  • Significantly reduced fractional anisotropy (FA) in ET patients.
  • FA reductions observed in the pons, cerebellum, midbrain, and deep WM.
  • Extensive WM abnormalities found in the orbitofrontal, frontal, parietal, and temporal regions.

Conclusions:

  • Structural white matter (WM) changes are extensive in essential tremor (ET).
  • Findings support previous neuroimaging and pathologic studies of ET.
  • ET may involve widespread neurodegeneration beyond the cerebellum.