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Published on: March 22, 2012
Cerebral Aspergillus arteritis with bland infarcts: a report of two patients with poor outcome
Megha S Uppin1, Sundaram Challa, Shantveer G Uppin
1Department of Pathology, NIMS, Panjagutta, Hyderabad andhra Pradesh, India.
Abstract:
Two patients with cerebrovascular aspergillosis, in the form of arteritis, thrombosis and bland infarcts are reported. One patient had systemic lupus erythematosus with disseminated aspergillosis in lungs, kidneys and brain. The other patient was immunocompetent and had sphenoid sinusitis. Both the patients were diagnosed at autopsy only, despite extensive imaging and laboratory studies. High index of clinical suspicion and early aggressive antifungal therapy are required since definite diagnostic modalities are not available.
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