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Transferrin is a growth factor for the bloodstream form of Trypanosoma brucei
D Schell1, N K Borowy, P Overath
1Max-Planck-Institut für Biologie, Abteilung Membranbiochemie, Tübingen, Federal Republic of Germany.
Parasitology Research
|January 1, 1991
Abstract:
A method for the selective depletion of transferrin from bovine serum is presented. Bloodstream forms of Trypanosoma brucei cannot grow in medium containing transferrin-deficient serum, whereas reconstitution with transferrin restores normal growth. We conclude that transferrin is an essential growth factor for the mammalian stage of the parasite.