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Prosthetic joint replacement for long bone metastases: analysis of 154 cases
F Camnasio1, C Scotti, G M Peretti
1Department of Orthopaedics and Traumatology, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy. camnasio.francesco@hsr.it
Archives of Orthopaedic and Trauma Surgery
|October 9, 2007
Summary
Prosthetic replacement for bone metastases offers improved quality of life and limb function. This surgical approach can enhance survival rates in selected patients with metastatic bone disease.
Area of Science:
- Orthopedic Oncology
- Skeletal Metastasis Management
- Prosthetic Reconstruction
Background:
- Metastatic bone disease is a common skeletal malignancy in adults, often treated palliatively.
- Treatment aims to control pain and prevent pathological fractures.
- Surgical resection of single bone metastases can improve survival in select cases.
Observation:
- A retrospective review of 154 patients (95 female, 59 male) treated with prosthesis for metastatic bone disease.
- Lower limb involvement (117 cases) was more common than upper limb (37 cases).
- Breast and renal carcinoma were the predominant primary sites (66%).
Findings:
- Follow-up ranged from 6 months to 12 years (median 26 months).
- One, two, and five-year survival rates were 69.5%, 44.8%, and 19.5%, respectively.
- Good or excellent functional results were achieved in 73.8% (proximal femur), 50% (knee), and 30.6% (proximal humerus).
Implications:
- Prosthetic replacement provides satisfactory results with low complication rates.
- Definitive treatment and fracture prevention improve quality of life and reduce local recurrence.
- Radical surgical intervention with prosthetics can enhance life expectancy and limb functionality.