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Related Concept Videos

Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Allergic Reactions02:06

Allergic Reactions

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Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
07:38

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Anisakis simplex allergy and nephrotic syndrome.

J Meseguer1, V Navarro, I Sánchez-Guerrero

  • 1Allergy Section, Sta. María del Rosell Hospital, Cartagena, Spain. jos_arc@ono.com

Allergologia Et Immunopathologia
|October 10, 2007
PubMed
Summary

Anisakis simplex allergy can cause nephrotic syndrome. This case study links raw fish consumption to allergic reactions and kidney disease, highlighting a novel association.

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Area of Science:

  • Clinical immunology
  • Parasitology
  • Nephrology

Background:

  • Anisakis simplex is a fish and shellfish parasite causing allergic reactions in humans.
  • Nephrotic syndrome is a kidney disorder that can be linked to parasitic infections like schistosomiasis.

Observation:

  • A 60-year-old woman developed nephrotic syndrome after experiencing urticaria, angioedema, and nausea post-raw anchovy ingestion.
  • Diagnostic evaluations included allergy testing, IgE level determination, immunoblotting, and HLA typing.

Findings:

  • The patient tested positive for Anisakis simplex allergy via prick-test.
  • Elevated total IgE levels and specific IgE to Anisakis simplex (>100 UI/ml) were detected.
  • Immunoblotting identified IgE-binding proteins in Anisakis simplex extracts.

Implications:

  • This study suggests a potential link between Anisakis simplex allergy and the development of nephrotic syndrome.
  • It underscores the importance of considering parasitic allergies in unexplained nephrotic syndrome cases.
  • Further research is warranted to elucidate the mechanisms behind this association.