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Updated: Jul 11, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Return to exercise training after heat exhaustion
Lawrence E Armstrong1, Rebecca M Lopez
1Department of Kinesiology, University of Connecticut, Storrs, CT, USA. lawrence.armstrong@uconn.edu
Context:
Exertional heat exhaustion (HEX) is the most common form of heat illness experienced by athletes, laborers, and military personnel. Both dehydration stemming from a water and/or salt deficiency and a high ambient temperature must exist for HEX to occur. In the field, appropriate therapy can reduce recovery time.
Objective:
This manuscript provides clinical guidance regarding return to activity. The primary focus of this paper is to describe the evaluation of residual effects and the underlying personal characteristics that initially predispose the athlete to HEX. Attention to these factors will reduce the risk of future episodes.
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