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Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Primary synovial sarcoma of the thyroid gland
Ki Seok Jang1, Kyueng Whan Min, Si Hyong Jang
1Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
Journal of Korean Medical Science
|December 6, 2007
Summary
This report details an extremely rare case of synovial sarcoma in a 15-year-old
Area of Science:
- Oncology
- Pathology
Background:
- Synovial sarcoma is a rare soft tissue neoplasm typically affecting young adults.
- Primary synovial sarcoma of the thyroid gland is exceptionally rare, with only one prior reported case.
Observation:
- A 15-year-old male presented with a palpable neck mass.
- Computed tomography revealed a well-demarcated solid mass within the left thyroid gland.
- Histological examination confirmed a biphasic synovial sarcoma.
Findings:
- Immunohistochemical, ultrastructural, and genetic studies supported the diagnosis of synovial sarcoma.
- The tumor was a large, solid mass measuring 6x5x5 cm.
Implications:
- Diagnosing synovial sarcoma in unusual locations like the thyroid presents significant challenges.
- Distinguishing it from other spindle cell tumors requires advanced diagnostic techniques.
- Ultrastructural and cytogenetic analyses are crucial for definitive diagnosis of thyroid synovial sarcoma.
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