Acute myocardial infarction due to an acute type A aortic dissection involving the left main coronary artery

E S Zegers1, H R Gehlmann, F W A Verheugt

  • 1Department of Cardiology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

Insights

An uncommon cause of heart attack is Stanford type A aortic dissection extending into the coronary artery. This case highlights spontaneous dissection involving the aorta and coronary artery, requiring emergent surgery.

Area of Science:

  • Cardiovascular Medicine
  • Thoracic Surgery
  • Interventional Cardiology

Background:

  • Stanford type A aortic dissection can rarely involve coronary arteries, leading to myocardial infarction.
  • Spontaneous aortic dissection, particularly involving the Valsalva sinus and ascending aorta, presents a significant clinical challenge.

Purpose of the Study:

  • To report a rare case of anterior myocardial infarction secondary to Stanford type A aortic dissection involving the left main coronary artery.
  • To discuss the pathophysiology and management of aortocoronary dissection in the context of aortic dissection.

Main Methods:

  • Case report detailing a patient with spontaneous aortic dissection.
  • Review of clinical presentation, diagnostic findings, and surgical intervention.

Main Results:

  • The patient presented with anterior myocardial infarction attributed to dissection extending into the left main coronary artery.
  • Successful surgical management involved emergent aortic replacement and coronary revascularization.

Conclusions:

  • Acute myocardial infarction from aortic dissection extension is infrequent but critical.
  • Spontaneous aortocoronary dissection, linked to hypertension, necessitates prompt surgical intervention.

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Coronary Circulation01:21

Coronary Circulation

The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...