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10:35
Production and Testing of Antimicrobial Peptides and Their Mimics
Published on: April 10, 2026
Tuning the membrane selectivity of antimicrobial peptides by using multivalent design
Zhigang Liu1, Anne W Young, Po Hu
1Department of Chemistry, New York University, 100 Washington Square East, New York, NY 10003, USA.
Chembiochem : a European Journal of Chemical Biology
|October 10, 2007
Summary
No abstract available in PubMed .
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Detergents are used to purify the integral proteins of the membrane. The hydrophobic portion of the detergent can replace membrane phospholipids while solubilizing the membrane proteins. When detergent monomers reach a specific concentration in a solution called critical micelle concentration (CMC), they form micelles. Above CMC, the concentration of the detergent monomers remains in equilibrium with the micelle. The number of detergent monomers present in the CMC varies for each detergent, and...

