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The association of opium with coronary artery disease
Saeed Sadeghian1, Soodabeh Darvish, Gholamreza Davoodi
1Tehran Heart Center, Tehran University of Medical Sciences, Jalal AL-Ahmad & North Kargar Cross, Tehran, Iran. sadeghian15@yahoo.com
Background:
The effects of opium consumption on coronary artery disease are still unknown.
Methods:
A cross-sectional study was conducted on 2405 patients admitted to the Angiographic Ward at Tehran Heart Center from 7 May 2005 to 13 August 2005.
Results:
After adjusting for conventional cardiovascular risk factors, opium consumption was a significant risk factor for coronary artery disease (P=0.01 and odds ratio=1.8). Moreover, the amount of opium consumption was associated significantly with the severity of coronary atherosclerosis, as measured by clinical vessel score (r=0.2, P=0.002).
Conclusions:
To our knowledge, this is the first time that the adverse effects of opium consumption on coronary arteries was defined.
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