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Updated: Jul 11, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
[Association of tracheobronchopathia osteochondroplastica and ozène]
1Service de Pneumologie, CHU Bretonneau, Tours, France. magro@med.univ-tours.fr
Introduction:
We report a case of tracheobronchopathia osteochondroplastica associated with Ozena (atrophic rhinitis).
Observation:
Fibreoptic bonchoscopy showed irregular tracheal stenosis and histopathological examination displayed zones of bone metaplasia in the tracheal submucosa. We isolated the bacteria Klebsiella pneumoniae sp ozaenae from bronchial aspirate.
Conclusion:
This organism is frequently isolated in both conditions suggesting some link between the two diseases.
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