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[Microvascular disease in diabetics--discrimination analysis of risk factors]
M Ilić1, H Vlajinac, J Marinković
1University School of Medicine, Kragujevac.
Insights
This study found that macrovascular disease is common in diabetic patients. Female diabetic patients with early onset diabetes and high diastolic blood pressure were more prone to vascular heart disease.
Area of Science:
- Cardiology
- Endocrinology
- Public Health
Context:
- Focuses on 206 diabetic patients aged 35-54 from urban Kragujevac.
- Investigates the prevalence of macrovascular complications in this cohort.
- Examines potential risk factors associated with these complications.
Purpose:
- To identify the prevalence of macrovascular disease in diabetic patients.
- To analyze risk factors contributing to macrovascular and specifically vascular heart disease.
- To understand demographic and clinical predictors in a Serbian urban population.
Summary:
- 40.3% of diabetic patients exhibited macrovascular disease, including vascular heart disease (34.9%), diseased leg blood vessels (12.1%), and cerebral stroke (2.4%).
- Discriminant analysis identified key risk factors: age, sex, BMI, smoking, blood pressure, glycemic control, lipid profiles, and diabetes history.
- Macrovascular and vascular heart disease were more prevalent in females with early-onset diabetes and elevated diastolic blood pressure.
Impact:
- Highlights the significant burden of macrovascular disease in diabetic populations.
- Provides insights into specific risk factors for targeted interventions.
- Informs public health strategies for diabetes management and cardiovascular risk reduction in Serbia.
Abstract:
The study concerned 206 diabetic patients, aged 35-54 years, from the urban Kragujevac area. Of this number 40.3 per cent had macrovascular disease, including vascular heart disease (34.9%), diseased leg blood vessels (12.1%) and cerebral stroke (2.4%). According to the results of discriminative analysis of potential risk factors (age, sex, body weight index, cigarette smoking, systolic and diastolic blood pressure, glycemia, triglycerides, lipoproteins, total cholesterol, HDL and LDL cholesterol, onset and duration of diabetes, family history) diabetic patients with macrovascular disease and patients with vascular heart disease predominated in female population with early onset of diabetes and high level of diastolic blood pressure.