[Hemostatic homeostasis in rheumatoid arthritis patients after "radiosynoviorthesis" with radioactive gold]

Six to nine months (7.2 months, on the average) after injection of 198Au into large joints of patients with rheumatoid arthritis there was a decrease of blood thrombophilia characteristics of these patients and refractory to correction with conventional remedies. Functional activity of platelets and fibrinolysis studies were the most sensitive laboratory tests enabling one to reveal the lowering of the patients' blood thrombogenic potential after radionuclide therapy. Comparison of the time-course of changes in these parameters with those of the immunological blood status of the treated patients forms the basis for suggestions that the coagulologic laboratory tests may be used for estimating the efficacy of the treatment carried out.