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Updated: Jul 11, 2026

Quantifiable and Inexpensive Cell-Free Fluorescent Method to Confirm the Ability of Novel Compounds to Chelate Iron
Published on: February 23, 2024
Deferiprone: second-line treatment of iron overload in the absence of a better alternative
Abstract:
Deferiprone is only a second-line option for the treatment of iron overload. The convenience of oral intake does not compensate for the lack of evidence concerning effects on morbidity and/or mortality. In contrast, deferoxamine, an injectable product, has proven clinical efficacy. However, seven years after initial marketing of deferiprone, its adverse effects (mainly neutropenia and agranulocytosis) are now better documented.
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