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Updated: Jul 11, 2026
09:43
Functional and Morphological Assessment of Diaphragm Innervation by Phrenic Motor Neurons
Published on: May 25, 2015
[Phrenic nerve paralysis following lung transplantation]
Yoshifumi Sano1, T Oto, S Toyooka
1Department of Cancer and Thoracic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Kyobu Geka. the Japanese Journal of Thoracic Surgery
|October 12, 2007
Summary
Phrenic nerve paralysis occurred in 8.2% of lung transplant recipients. While generally transient, this complication necessitates careful surgical technique to prevent nerve injury during lung transplantation.
Area of Science:
- Thoracic Surgery
- Neurosurgery
- Pulmonary Medicine
Context:
- Phrenic nerve paralysis is a known complication of cardiac surgery.
- It is less frequently reported following lung transplantation.
- This study examines its incidence and outcomes in lung transplant recipients.
Purpose:
- To determine the incidence of phrenic nerve paralysis after lung transplantation.
- To assess the clinical outcomes and recovery of patients experiencing this complication.
- To identify potential causes and preventive strategies for phrenic nerve injury during lung transplantation.
Summary:
- A retrospective study of 49 lung transplantations identified phrenic nerve paralysis in 4 patients (8.2%), affecting unilateral or bilateral nerves.
- All identified cases showed transient recovery.
- While not statistically significant, patients with phrenic nerve paralysis tended to have longer durations of ventilation, ICU stay, and hospitalization.
Impact:
- Highlights the incidence of phrenic nerve paralysis in lung transplantation.
- Suggests potential iatrogenic causes including dissection, electrocautery, and hypothermia.
- Emphasizes the importance of meticulous surgical technique to avoid phrenic nerve injury during lung transplant procedures.
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