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[Antipsychotics and sexual functioning in persons with psychoses].
H Knegtering1, R Bruggeman, S Castelein
1h.knegtering@psy.umcg.nl
Tijdschrift Voor Psychiatrie
|October 12, 2007
Summary
Antipsychotic medications frequently cause sexual dysfunction, affecting libido, arousal, and orgasm in 30-60% of patients. Addressing these issues with clinicians can lead to effective management strategies.
Area of Science:
- Pharmacology
- Neuroscience
- Sexual Medicine
Context:
- Limited research exists on antipsychotic-induced sexual dysfunction.
- Recent advancements provide clinically relevant information.
- Sexual side effects impact patient quality of life and treatment adherence.
Purpose:
- To detail the frequency, nature, and causes of sexual dysfunction during antipsychotic treatment.
- To propose clinical strategies for managing these dysfunctions.
- To review underlying mechanisms and potential interventions.
Summary:
- Antipsychotics are linked to sexual dysfunctions (loss of libido, erectile/lubrication issues, orgasm/ejaculation disorders) in 30-60% of cases.
- High dopamine receptor affinity and elevated prolactin levels are associated with frequent sexual side effects.
- Underreporting is common without active clinical intervention.
Impact:
- Clinicians can manage sexual dysfunction through education, medication adjustment, or supplementary treatments.
- Proactive management improves patient outcomes and treatment compliance.
- Understanding these effects is crucial for comprehensive psychiatric care.
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