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Updated: Jul 11, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
[Migraine and cardiovascular risk]
G M Terwindt1, J Haan, H Koppen
1Leids Universitair Medisch Centrum, afd. Neurologie, Postbus 9600, 2300 RC Leiden. g.m.terwindt@lumc.nl
Migraine, particularly migraine with aura, is linked to a higher relative risk of cardiovascular disease. However, absolute risks remain low, and further research is needed to confirm causality and treatment effects.
Area of Science:
- Neurology
- Epidemiology
- Cardiology
Context:
- Emerging epidemiological data indicate a potential association between migraine and cardiovascular disease (CVD).
- Migraine with aura presents a notable focus in this observed relationship.
- The absolute risk of CVD in migraineurs is low, despite a 2-4 fold increased relative risk.
Purpose:
- To explore the epidemiological evidence linking migraine and cardiovascular disease.
- To investigate whether migraine serves as an independent risk factor for CVD.
- To determine if prophylactic migraine treatment can mitigate associated CVD risks.
Summary:
- Epidemiological studies suggest a correlation between migraine, especially migraine with aura, and cardiovascular disease.
- While relative risk is elevated (2-4 fold), the absolute risk for cardiovascular disease in migraine patients remains low.
- Further investigation is required to establish migraine as an independent CVD risk factor and assess the impact of prophylactic treatments.
Impact:
- Highlights the need for further research into the migraine-CVD link.
- Informs clinical practice regarding cardiovascular risk assessment in migraine patients.
- Potential implications for therapeutic strategies in migraine management and CVD prevention.
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