Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Population Growth00:57

Population Growth

Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.However, realistic environmental conditions limit the number of...
What are Populations and Communities?00:30

What are Populations and Communities?

Populations are groups of individuals of the same species that inhabit a shared environment. Communities include multiple co-existing, interacting populations of different species. Metapopulations span multiple populations of the same species that occupy different areas. Metapopulations interact through immigration and emigration, providing genetic diversity that lends resilience to harsh environments. Population size and density can be estimated using quadrat and mark and recapture...
Mutation, Gene Flow, and Genetic Drift01:09

Mutation, Gene Flow, and Genetic Drift

In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).Mechanisms of Genetic VariationThe original sources of genetic variation are mutations,...
Hybrid Zones02:29

Hybrid Zones

Hybrid zones are narrow regions where two closely related species interact, mate, and produce hybrids. Relative to either parent species, hybrids may possess distinct phenotypic or genetic differences that impact their survival and reproductive success. The genetic variances introduced by hybridization influence species diversity and speciation processes within the hybrid zone.Gene flow and natural selection are evolutionary mechanisms that shape the outcome of a hybrid zone. Gene flow...
Gene Flow02:39

Gene Flow

Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adaptive multi-model ensembles for improved epidemic projections and decision support.

medRxiv : the preprint server for health sciences·2026
Same author

Mobility data resolution needed to inform predictive models of spatial epidemic spread from mobile phone data.

PLoS computational biology·2026
Same author

Estimating importation risk of Bundibugyo Ebola virus disease to Europe under different outbreak expansion scenarios.

Journal of travel medicine·2026
Same author

International risk of secondary hantavirus clusters following MV Hondius outbreak.

Journal of travel medicine·2026
Same author

Mapping the landscape of individual-based models for respiratory pathogen transmission in the pandemic and post-pandemic era (2020-2024): A systematic review.

Epidemics·2026
Same author

Resetting population mobility responses under repeated nonpharmaceutical interventions: Implications for hypothesized pandemic fatigue.

Proceedings of the National Academy of Sciences of the United States of America·2026

Related Experiment Video

Updated: Jul 11, 2026

Monitoring Spatial Segregation in Surface Colonizing Microbial Populations
07:40

Monitoring Spatial Segregation in Surface Colonizing Microbial Populations

Published on: October 29, 2016

Invasion threshold in heterogeneous metapopulation networks.

Vittoria Colizza1, Alessandro Vespignani

  • 1Complex Networks Lagrange Laboratory, Institute for Scientific Interchange, Torino, Italy.

Physical Review Letters
|October 13, 2007
PubMed
Summary

We identified a global invasion threshold for epidemics in connected populations. Below this critical mobility rate, widespread outbreaks are prevented, offering insights into travel restrictions for containment.

More Related Videos

Experimental Protocol for Manipulating Plant-induced Soil Heterogeneity
08:16

Experimental Protocol for Manipulating Plant-induced Soil Heterogeneity

Published on: March 13, 2014

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling
20:36

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

Related Experiment Videos

Last Updated: Jul 11, 2026

Monitoring Spatial Segregation in Surface Colonizing Microbial Populations
07:40

Monitoring Spatial Segregation in Surface Colonizing Microbial Populations

Published on: October 29, 2016

Experimental Protocol for Manipulating Plant-induced Soil Heterogeneity
08:16

Experimental Protocol for Manipulating Plant-induced Soil Heterogeneity

Published on: March 13, 2014

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling
20:36

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

Area of Science:

  • Epidemiology
  • Mathematical Biology
  • Network Science

Background:

  • Metapopulation models are crucial for understanding disease spread across connected subpopulations.
  • Heterogeneous connectivity patterns significantly influence epidemic dynamics.
  • Reaction-diffusion processes model the interplay between local spread and spatial movement.

Purpose of the Study:

  • To investigate epidemic dynamics in metapopulation models with complex network structures.
  • To identify and characterize a global invasion threshold beyond the local epidemic threshold.
  • To provide a framework for analyzing the impact of mobility on epidemic containment.

Main Methods:

  • Analysis of susceptible-infected-removed (SIR)-like processes on networks.
  • Derivation of an explicit expression for the global invasion threshold.
  • Examination of the influence of topological fluctuations in metapopulation networks.

Main Results:

  • A global invasion threshold exists in addition to the local epidemic threshold.
  • This threshold depends critically on the diffusion/mobility rate.
  • Topological properties of the metapopulation network influence the invasion threshold.

Conclusions:

  • The global invasion threshold dictates the minimum mobility required for a disease to spread widely.
  • Understanding this threshold is key to evaluating the effectiveness of travel restrictions.
  • The study offers a general framework for epidemic containment strategies in networked populations.