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Updated: Jul 10, 2026

Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
Published on: May 29, 2020
Current topics relating to autoimmune hepatitis diagnosis and therapy
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, JIEKI University School of Medicine, Tokyo, Japan.
Abstract:
Autoimmune hepatitis (AIH) was first reported by Professor Ian R. Mackay. Environmental factors (such as viral infection), chemical substances (including some drugs) and genetic factors (such as human leukocyte antigen-DR) are believed to participate in the pathogenesis of AIH. Because satisfactory prognosis depends upon the patient being diagnosed with AIH correctly and receiving proper therapy immediately, it isvery important to make a correct diagnosis and perform the suitable therapy as soon as possible. In this review, current topics relating to AIH diagnosis and therapy are summarized.
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