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Published on: February 28, 2013
Cardiovascular risk factors and their management in 1282 adult people with type 1 diabetes
Ateeq Syed1, Sania Hussain, Peter Nightingale
1University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Insights
Cardiovascular disease risk factors are poorly managed in adults with type 1 diabetes (T1D) in the UK. Aggressive management is crucial to reduce T1D mortality rates.
Area of Science:
- Endocrinology
- Cardiology
- Public Health
Background:
- Type 1 diabetes (T1D) significantly increases mortality risk, primarily due to cardiovascular disease (CVD).
- Established guidelines aim to mitigate CVD risk factors in T1D patients.
- This study assesses adherence to current CVD risk management guidelines in a UK T1D population.
Purpose of the Study:
- To evaluate the achievement of CVD risk factor guidelines in adults with T1D.
- To identify gaps in the recording and management of CVD risk factors.
Main Methods:
- A retrospective audit of 1282 adults with T1D in Birmingham, UK.
- Assessment against Joint British Societies guidelines: blood pressure (BP) ≤130/80 mmHg, total cholesterol (TC) ≤4 mmol/L, non-smoking status, HbA(1c) ≤6.5%, and body mass index (BMI) ≤25 kg/m².
- Data collection focused on documentation and achievement of these targets.
Main Results:
- CVD risk factor data were poorly documented; only 72% had complete records for TC, smoking, and HbA(1c).
- Only 0.7% of patients achieved all minimal dataset targets.
- HbA(1c) and TC targets were the least frequently met.
Conclusions:
- CVD risk factors are inadequately recorded and sub-optimally managed in UK adults with T1D.
- Current management strategies fall short of recommended guidelines.
- More intensive management is essential to lower the high mortality rates associated with T1D.
Objective:
The mortality rate in people with type 1 diabetes (T1D) is over three-times that of their counterparts without diabetes. The underlying reason for this in the developed world is cardiovascular disease (CVD). Strict control of CVD risk factors, for which guidelines now exist, reduces morbidity and mortality. The objective of this study was to determine if these guidelines are being achieved.
Research Design:
Data were collected on 1282 adults with T1D from hospitals in the city of Birmingham, UK. Guidelines were those recommended by Joint British Societies: blood pressure (BP) 130/80 mmHg, total cholesterol (TC) 4 mmol/L, non-smoking status, HbA(1c) 6.5% and body mass index (BMI) 25 kg/m(2).
Main Outcome Measures:
The mean age was 46 years and duration of diabetes 21 years. Data on CVD risk factors were poorly documented, with a minimally defined dataset of TC, smoking history and HbA(1c) being completely recorded in only 72% of people. CVD risk factor targets were also poorly achieved with only 0.7% of patients achieving all minimal dataset targets. HbA(1c) and TC targets were those most poorly achieved.
Conclusions:
This is the largest study of CVD risk factors in the UK and the only one to audit the standard of care provided against recent guidelines published by the joint societies. The results show that CVD risk factors are poorly recorded and sub-optimally managed in adults with T1D. Far more aggressive management is essential if mortality rates for T1D in the UK are to be reduced.
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