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Related Experiment Videos

Left ventricular pacing by automatic capture verification.

Mauro Biffi1, Matteo Bertini, Matteo Ziacchi

  • 1Institute of Cardiology, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. mauro.biffi@aosp.bo.it

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
|October 13, 2007
PubMed
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This study demonstrates the long-term feasibility and safety of transvenous left ventricular (LV) pacing with autocapture. Continuous monitoring of LV evoked response (ER) ensures reliable capture verification for automatic pacemaker output adjustment.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Devices

Background:

  • Transvenous left ventricular (LV) pacing requires reliable capture verification for safe and effective automatic output adjustment.
  • Beat-to-beat detection of LV evoked response (ER) is crucial for autocapture functionality.

Purpose of the Study:

  • To assess the long-term feasibility and safety of transvenous LV pacing utilizing autocapture technology.
  • To evaluate the reliability of LV evoked response (ER) measurement for automatic pacemaker output adjustment.

Main Methods:

  • Seven patients received DDDR pacemakers with automatic output adjustment and LV leads placed in the coronary sinus.
  • The system performed LV threshold trending and threshold tests every 21 hours, monitoring ER detection.
  • Follow-up averaged 34 months, assessing LV pacing thresholds and autocapture performance.

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Main Results:

  • LV pacing thresholds initially increased but returned to baseline within 7 weeks.
  • Autocapture performance remained stable long-term, with no critical issues in ER detection.
  • The system effectively managed LV threshold variations and ensured consistent pacing capture.

Conclusions:

  • Transvenous LV pacing with autocapture is feasible and safe for long-term use.
  • Capture verification during LV pacing alone is reliable.
  • This technology holds potential for biventricular stimulation applications.