Related Experiment Video
Updated: Jul 10, 2026

07:35
A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
Published on: July 5, 2017
Relationship between refraction and allergic conjunctivitis.
T Mimura1, Y Mimura, A Arimoto
1Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan. mimurat-tky@umin.ac.jp
Eye (London, England)
|October 13, 2007
Summary
Refractive error, such as myopia, may increase the risk of developing allergic conjunctivitis in non-contact lens wearers. This study explored the link between eye biometrics and this common allergy.
Area of Science:
- Ophthalmology
- Allergy Research
- Biometry
Background:
- Allergic diseases are primarily caused by external allergens.
- Internal factors, like ocular biometrical structure, are less understood in allergic conjunctivitis pathogenesis.
Purpose of the Study:
- Investigate the relationship between refractive error and allergic conjunctivitis.
- Explore potential internal risk factors for allergic conjunctivitis.
Main Methods:
- Analyzed 1015 subjects, categorized by contact lens wear and allergic conjunctivitis status.
- Measured refractive error parameters: spherical power, cylindrical power, corneal radius, and corneal refractive powers.
Main Results:
- Non-contact lens wearers with allergic conjunctivitis showed significantly lower spherical equivalent and spherical power compared to those without.
- No significant differences in refractive parameters were found between contact lens wearers with and without allergic conjunctivitis.
Conclusions:
- Refractive error, particularly myopia, may serve as a risk factor for allergic conjunctivitis.
- Findings suggest a potential link between specific refractive states and the development of allergic conjunctivitis.
More Related Videos
Related Concept Videos
Focusing of Light in the Eye
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Allergic Reactions: Anaphylaxis
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Reactions
Overview
Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Microbiome of the Eye
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

