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Updated: Jul 10, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
Presumed infective meningoencephalitis complicated by bilateral optic neuritis
D M Gore1, G D Hildebrand, R Sekhri
1Department of Ophthalmology, Great Ormond Street Hospital, London, UK. danielmgore@gmail.com
A severe case of presumed infective meningoencephalitis in a child led to bilateral optic neuritis. Prompt corticosteroid treatment improved vision and neurological deficits.
Area of Science:
- Neurology
- Ophthalmology
- Infectious Diseases
Background:
- Meningoencephalitis can present with diverse neurological complications.
- Optic neuritis is a significant cause of visual impairment.
Observation:
- A 7-year-old girl with presumed infective meningoencephalitis developed altered consciousness, hemiplegia, and severe bilateral optic neuritis.
- Standard antimicrobial and antiviral therapies were ineffective.
Findings:
- High-dose systemic corticosteroids were initiated due to the patient's deterioration.
- The patient showed recovery of optic nerve function and resolution of hemiplegia after corticosteroid administration.
Implications:
- This case highlights the potential for severe optic neuritis in meningoencephalitis.
- Early and aggressive corticosteroid therapy may be crucial for preserving vision in such cases.
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