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Published on: May 22, 2026
Depression and anxiety in children at the end of life
Leslie S Kersun1, Eyal Shemesh
1Division of Oncology, The Children's Hospital of Philadelphia, 4th Floor Wood Building, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA. segall@email.chop.edu
Insights
Prompt diagnosis and management of anxiety and depression in children receiving palliative care are crucial. Recognizing and addressing these symptoms can significantly improve end-of-life care for pediatric patients.
Area of Science:
- Palliative Care
- Pediatric Oncology
- Child Psychology
Background:
- Anxiety and depression are common in children requiring palliative care.
- Effective management of these conditions is essential for quality of life.
Purpose of the Study:
- To review the symptoms and treatment of anxiety and depressive disorders in end-of-life pediatric patients.
- To highlight challenges and considerations in diagnosis and management.
Main Methods:
- Literature review of anxiety and depressive disorders in pediatric palliative care.
- Discussion of diagnostic challenges, communication, and suicidality.
- Examination of available treatment options and their risks/benefits.
Main Results:
- Distinguishing symptoms from disorders is key.
- Child's understanding of death and communication are important factors.
- Screening, diagnosis, and treatment approaches require careful consideration.
Conclusions:
- Recognizing and addressing anxiety and depression symptoms is imperative.
- Informed management strategies improve care for children at end of life.
- Available treatments necessitate a balanced risk-benefit approach.
Abstract:
A significant component of palliative care is the prompt diagnosis and management of distress, anxiety, and depression. This article reviews the symptoms and treatment of anxiety and depressive disorders in children at the end of life. Distinguishing between symptoms and disorders, the importance of open communication, consideration of the child's understanding of death, diagnostic challenges in chronically ill children, and suicidality are discussed. Because treatment options are available, it is imperative that symptoms are recognized and addressed. Understanding the issues involved in screening and diagnosis and the risks and benefits of available treatments can lead to an informed approach to the management of these disorders in the palliative care setting.
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