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The spotted nephrogram of renal scleroderma.

J Winograd, D H Schimmel, A J Palubinskas

    AJR. American Journal of Roentgenology
    |April 1, 1976
    PubMed
    Summary
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    Scleroderma can cause hypertension due to subtle renal artery changes. A spotted nephrogram, without major arterial damage, strongly suggests kidney involvement in scleroderma.

    Area of Science:

    • Nephrology
    • Radiology
    • Rheumatology

    Background:

    • Scleroderma is an autoimmune disease that can affect multiple organs, including the kidneys.
    • Hypertension is a common complication of scleroderma, often indicating renal involvement.

    Observation:

    • Two patients with scleroderma and recent-onset hypertension were evaluated using renal angiography.
    • Angiography revealed minor changes in the distal interlobar and arcuate arteries.

    Findings:

    • A distinctive "spotted" nephrogram was observed in both patients.
    • This finding, in the absence of significant arterial stenosis, is highly indicative of renal scleroderma.

    Implications:

    • The "spotted nephrogram" may serve as a crucial diagnostic marker for renal scleroderma.

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  • Early identification can lead to timely intervention and management of hypertensive complications in scleroderma patients.