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Updated: Jul 10, 2026

Ferric Chloride-induced Murine Thrombosis Models
Published on: September 5, 2016
New therapies for immune thrombocytopenic purpura
Biree Andemariam1, James Bussel
1Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York, USA.
Purpose Of Review:
The treatment landscape of immune thrombocytopenic purpura has the potential for dramatic change in the near future as promising new agents and adaptations of older therapies enter clinical study. An update on the status of current research in immune thrombocytopenic purpura and a preview of agents in development are provided here.
Recent Findings:
The recent literature shows a multitude of strategies employed in the treatment of immune thrombocytopenic purpura. These therapies under active investigation include the use of the B-cell-depleting monoclonal antibody rituximab, higher doses of dexamethasone and anti-D immunoglobulin, and thrombopoiesis-stimulating agents that are in early clinical development.
Summary:
Clinical investigation of novel therapies in immune thrombocytopenic purpura is undergoing a revolution that has the potential to change the standard of care. While older therapies are experiencing a rebirth by being given a new spin, newer agents such as thrombopoietins are showing significant promise.
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