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Related Experiment Video

Updated: Jul 10, 2026

Thrombus Profiling Assay: A Microfluidics-Based Platform for Comprehensively Characterizing Biomechanical Thrombogenesis

Thrombus Profiling Assay: A Microfluidics-Based Platform for Comprehensively Characterizing Biomechanical Thrombogenesis

Published on: January 9, 2026

Is screening for thrombophilia cost-effective?

Olivia Wu¹, Ian A Greer

¹Public Health and Health Policy, University of Glasgow, Glasgow, UK.

Current Opinion in Hematology

|October 16, 2007

Summary

This summary is machine-generated.

Screening for thrombophilia (a condition increasing venous thromboembolism risk) is generally not cost-effective. Selective screening is more economical than universal approaches, but refined strategies may improve value.

Related Experiment Videos

Last Updated: Jul 10, 2026

Thrombus Profiling Assay: A Microfluidics-Based Platform for Comprehensively Characterizing Biomechanical Thrombogenesis

Thrombus Profiling Assay: A Microfluidics-Based Platform for Comprehensively Characterizing Biomechanical Thrombogenesis

Published on: January 9, 2026

Area of Science:

Medical Economics
Hematology
Public Health

Background:

Thrombophilia significantly elevates the risk of venous thromboembolism (VTE).
Evaluating the economic impact of VTE screening is crucial for healthcare resource allocation.

Purpose of the Study:

To review existing evidence on the cost-effectiveness of thrombophilia screening.
To identify factors influencing the economic viability of different screening strategies.

Main Methods:

Systematic review of studies assessing the cost-effectiveness of thrombophilia screening.
Analysis of direct medical costs associated with detecting thrombophilia and preventing VTE.

Main Results:

Few studies have evaluated thrombophilia screening cost-effectiveness.
Selective, history-based screening is more cost-effective than universal screening.
Screening women before combined oral contraceptives is the least cost-effective strategy.

Conclusions:

Current evidence suggests thrombophilia screening is unlikely to be cost-effective due to low absolute event numbers.
Refining screening through better risk assessment or global coagulation tests could enhance cost-effectiveness.
Further research into optimized screening protocols is warranted.