Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

ansa-Metallocene-based cyclic[2]pyrroles.

S Ramakrishnan1, Alagar Srinivasan

  • 1Photosciences and Photonics Section, Chemical Sciences and Technology Division, National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, Kerala, India.

Organic Letters
|October 16, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical practice guideline-inconsistent management of fever and neutropenia in pediatric oncology: A Children's Oncology Group study.

Pediatric blood & cancer·2024
Same author

Hyperbranched polymers: growing richer in flavours with time.

Chemical communications (Cambridge, England)·2024
Same author

LATCH Score: Bridging the Gap in the Observational Study: AUTHORS' REPLY.

Indian pediatrics·2023
Same author

Amphiphilic Polymer Hydrogel-supported Catalysts: Tuning the Accessibility to the Catalytic Site by Molecular Jacketing.

Chemistry, an Asian journal·2023
Same author

Removal of breast implants as primary treatment for autoimmune/inflammatory syndrome induced by adjuvants.

Scandinavian journal of rheumatology·2022
Same author

Muscle Fatigue Analysis by Visualization of Dynamic Surface EMG Signals Using Markov Transition Field.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2022
Same journal

Acid-Catalyzed Synthesis of C-6-Esterified Sugar Acceptors from Acetals/Ketals Using Esters as Acyl Donors.

Organic letters·2026
Same journal

Asymmetric Hydrophosphination of Quinolinones and Chromones Catalyzed by Chiral Phosphoric Acid.

Organic letters·2026
Same journal

Cellobiose-Derived β-Linked Disaccharide Donor Enables Convergent Syntheses of <i>Acinetobacter baumannii</i> K91 and K25 Capsular Trisaccharides.

Organic letters·2026
Same journal

Iodine-Mediated On-DNA Oxidative Cyclization of 2-Pyridylhydrazones for 1,2,4-Triazolo[4,3-<i>a</i>]pyridines.

Organic letters·2026
Same journal

Manipulating the Activity and Diastereoselectivity of ω-Transaminase for the Synthesis of Bulky Aminopiperidines with Contiguous Stereocenters.

Organic letters·2026
Same journal

Total Synthesis of Voratin C: Formation of the [6,5]-Spiroketal Core through Acid-Mediated Epoxide Cascade Opening.

Organic letters·2026
See all related articles

Syntheses of ansa-metallocene-based cyclic[2]pyrroles were achieved. X-ray structural analyses revealed that the pyrrole units in these macrocycles adopt a partial 1,2-alternate conformation in the solid state.

Area of Science:

  • Organometallic Chemistry
  • Supramolecular Chemistry
  • Crystallography

Background:

  • Ansa-metallocenes are versatile organometallic compounds with bridged structures.
  • Cyclic pyrrole derivatives are of interest in materials science and medicinal chemistry.
  • Understanding macrocyclic conformations is crucial for predicting molecular properties.

Purpose of the Study:

  • To synthesize novel ansa-metallocene-based cyclic[2]pyrroles.
  • To elucidate the solid-state structures of these macrocycles using X-ray diffraction.
  • To investigate the conformational preferences of pyrrole units within the macrocyclic framework.

Main Methods:

  • Chemical synthesis of ansa-metallocene precursors.
  • Cyclization reactions to form macrocycles.

Related Experiment Videos

  • Single-crystal X-ray diffraction analysis.

    • Main Results:

    • Successful synthesis of ansa-metallocene-based cyclic[2]pyrroles.
    • Detailed X-ray structural data obtained for the synthesized compounds.
    • Identification of a partial 1,2-alternate conformation for the pyrrole units in the solid state.

    Conclusions:

    • The study demonstrates the feasibility of constructing ansa-metallocene-based cyclic[2]pyrroles.
    • The conformational analysis provides insights into the structural diversity of metallocene macrocycles.
    • These findings contribute to the understanding of structure-property relationships in organometallic macrocycles.