Related Experiment Video
Updated: Jul 10, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Secondary pigmented macular pucker on optical coherence tomography
Carsten H Meyer1, Stefan Mennel, Jörg C Schmidt
1Department of Ophthalmology, Philipps University, Marburg, Germany.
Purpose:
To describe the clinical features, retinal architecture and tomographic configuration of a pigmented epiretinal membrane on optical coherence tomography (OCT).
Methods:
A 52-year-old man presented during a routine examination with an asymptomatic, darkly pigmented, pre-retinal epiretinal membrane in his right eye. His best corrected visual acuity (BCVA) on Snellen charts was 20/25 in the right eye and 20/20 in the left. The patient complained of no visual symptoms or metamorphopsia.
Results:
In the fundus periphery there was a small, old, well pigmented retinal hole with pigmentation in its immediate vicinity, without signs of vitreal traction, which required no treatment. The foveal indentation was not apparent on OCT and a well demarcated hyperreflective band defined the pigmented epiretinal membranes (ERMs). Sequential fundus examination over a 2-year period demonstrated no functional or anatomical deterioration attributable to the disease.
Conclusions:
Pigmented ERM may have different cellular origins depending on the underlying pathology. Patients with pigmented ERM and full VA should be followed by sequential OCT.

