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Updated: Jul 10, 2026

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Idioventricular rhythm induced by therapeutic hypothermia
En-Ting Wu1, Shu-Chien Huang, Nai-Hsin Chi
1Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Abstract:
We report the case of a 11-year-old girl with fulminant myocarditis and cardiogenic shock who received cardiopulmonary resuscitation and extracorporeal membrane oxygenation support. During the induction of hypothermia, her rhythm degenerated into idioventricular rhythm with extremely prolonged QRS duration. The hypothermia-induced bradycardia caused a drop of mixed venous oxygenation saturation and which was resolved by re-warming to normothermia. This finding suggested that hypothermia may compromise cardiac performance and physicians should be cautious about its application in patients with fulminant myocarditis.
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