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Updated: Jul 10, 2026

Ultrasound-based Pulse Wave Velocity Evaluation in Mice
Published on: February 14, 2017
Improving performance of pulse compression in a Doppler ultrasound system using amplitude modulated chirps and Wiener
Joanne Cowe1, John Gittins, David H Evans
1Department of Medical Physics, University Hospitals of Leicester NHS Trust, Leicester, UK. j.cowe@le.ac.uk
Abstract:
The use of coded excitation and pulse compression in transcranial Doppler (TCD) ultrasound systems is in the very early stages; the optimal processing scheme has yet to be determined. This study uses linear frequency-modulated (FM) chirps with 0.8-MHz bandwidth and compares the use of pulses with and without amplitude modulation and also matched filtering vs. Wiener filtering. The results demonstrate that using amplitude-modulated pulses vastly improves the axial resolution and provides a more predictable mainlobe-to-sidelobe distance in the radiofrequency (RF) signal. It is also shown that a Wiener filter can provide better performance than a matched filter, in terms of axial resolution and sidelobe level in the RF signal and signal-to-noise ratio in conventional sonograms. Although this study uses a TCD system, the techniques described are equally as applicable in other Doppler ultrasound devices.
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