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Updated: Jul 10, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
[Histopathological changes in pseudoexfoliative syndrome]
Mihaela Sollosy1, Mirela Preda, Cristina Simionescu
1Clinica de Oftalmologie Craiova.
Purpose:
The purpose of this study was to analyse the structural modifications of the anterior structures of the human eyes with exfoliation syndrome in optic microscopy.
Material And Method:
For this we used bulbar conjunctival fragments and the anterior part of the eyes who were eviscerated for the complications of exfoliative glaucoma. For the optic microscopy the human specimens were preserved in paraffin and stained with hematoxiline-eosine, PAS and Congo red method.
Results:
We have demonstrated in this study using this three coloration that the abnormal material is exfoliative material and not amyloid in all the ocular structures that were studied (conjunctiva, cornea, lens and ciliary body).
Conclusions:
All the anterior structures of the eyes that were examined present typical histopathological alterations of the exfoliation syndrome. The Congo red coloration demonstrate that the abnormal material present in all the structures that were examined is exfoliation material and not amyloid.
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