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Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction
16:23

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction

Published on: February 26, 2014

[First screening for behavioral phenotype of gene-engineered mice]

Atsushi Kasai1, Norihito Shintani

  • 1kasai@pharm.setsunan.ac.jp

Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica
|October 17, 2007
PubMed
Summary

No abstract available in PubMed .

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Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...