Chronic intestinal pseudo-obstruction in patients with systemic lupus erythematosus: report of four cases
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Updated: Jul 10, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
Federico Ceccato1, Adrián Salas, Vanina Góngora
1Rheumatology Section, Hospital JM Cullen, Santa Fe, Argentina.
Abstract:
Chronic intestinal pseudo-obstruction (CIPO), a recently recognized manifestation of systemic lupus erythematosus (SLE) with only 23 cases reported in the English literature, may appear as a complication or as the initial presentation of SLE and usually occurs during the setting of an active lupus. The pathogenic mechanism in SLE is unknown. We describe four additional cases with clinical, radiological, and manometric features of CIPO. As SLE-related CIPO usually responds to treatment with high doses of corticosteroids and/or immunosuppressive and prokinetic agents, a high level of awareness of this complication is needed to avoid unnecessary surgical intervention.
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