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Adamantinoma.

Panagiotis Kitsoulis1, Antonia Charchanti, Georgios Paraskevas

  • 1Department of Anatomy, Laboratory of Anatomy-Histology-Embryology, Medical School, University of Ioannina, Greece. pkitsoulis@hotmail.com

Acta Orthopaedica Belgica
|October 18, 2007
PubMed
Summary

Adamantinoma, a rare bone tumor, typically affects the long bones, especially the tibia. Current treatments focus on surgical excision, as radiation and chemotherapy are ineffective.

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Area of Science:

  • Orthopedics
  • Oncology
  • Pathology

Background:

  • Adamantinoma is an exceptionally rare, low-grade malignant bone tumor, accounting for less than 1% of all bone malignancies.
  • First described by Fisher in 1913, its name derives from its resemblance to jaw ameloblastoma.

Purpose of the Study:

  • To provide a comprehensive overview of adamantinoma, including its epidemiology, clinical presentation, and treatment.
  • To highlight the characteristic locations and rare occurrences of this bone tumor.

Main Methods:

  • Review of existing literature on adamantinoma.
  • Analysis of reported cases concerning tumor location, patient demographics, and treatment outcomes.

Main Results:

  • Adamantinoma predominantly affects long tubular bones, with the tibial midshaft being the most common site (80-85%).
  • Symptoms are often nonspecific, including swelling, redness, and pain.
  • Young males are more frequently diagnosed with adamantinoma than females.

Conclusions:

  • Adamantinoma requires surgical intervention, with options including wide excision and limb salvage or amputation.
  • Radiotherapy and chemotherapy have demonstrated limited efficacy in treating adamantinoma.

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