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Suspected isolated pancreatic lipase deficiency in a dog

Panagiotis G Xenoulis1, Jonathan M Fradkin, Steven W Rapp

  • 1Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA. pxenoulis@cvm.tamu.edu

Journal of Veterinary Internal Medicine
|October 18, 2007
PubMed
Abstract

No abstract available in PubMed .

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Acute Pancreatitis II: Pathophysiology01:21

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The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
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