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Updated: Jul 10, 2026

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
Multisignaling optical-electrochemical sensor for Hg2+ based on a rhodamine derivative with a ferrocene unit
Hong Yang1, Zhiguo Zhou, Kewei Huang
1Department of Chemistry & Laboratory of Advanced Materials, Fudan University, Shanghai, People's Republic of China.
Abstract:
A new multisignaling sensor based on rhodamine B with a ferrocene substituent (1) has been synthesized and has been shown to display extreme selectivity for Hg2+ over other metal ions. Multisignaling changes are observed through UV/vis absorption, fluorescence emission, and electrochemical measurements. Furthermore, by means of confocal laser scanning microscopy experiments, it is demonstrated that 1 can be used as a fluorescent probe for monitoring Hg2+ in living cells.
