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Updated: Jul 10, 2026

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data
Published on: April 18, 2019
Headache 22 years after hospitalization for head injury compared with matched community controls
1Norwegian Health Services Research Centre, Oslo, Norway. knut.nestvold@ahus.no
Objectives:
Little information is available on long-term headache following head injury. We compared the prevalence of headache in a cohort with previous hospitalization for head injury and matched controls.
Materials And Methods:
A questionnaire about headache was sent to 361 patients who were hospitalized for head injury in 1974-1975 and 722 matched community controls.
Results:
In multivariate conditional regression analysis among 192 responding case/control pairs, there was no evidence of higher odds of headache >or=1 day per month (odds ratio, OR 1.04, 95% CI 0.56-1.92, p = 0.90) compared with controls. However, there was a tendency to higher odds of headache >or=1 day per month among female cases than among controls (OR 2.03, 95% CI 0.94-4.39, p = 0.07).
Conclusions:
The study could not show increased odds of headache in a cohort 22 years following hospitalization for head injury, but it is possible that females are more likely to report long-term headache following head injury than matched controls.
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