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Related Concept Videos

Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists01:27

Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists

5-HT3 receptor antagonists, such as dolasetron, granisetron (Kytril), ondansetron (Zofran), and palonosetron (Axoli), are crucial in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea. These drugs selectively block 5-HT3 receptors in the visceral vagal and spinal afferent nerves, chemoreceptor trigger zone, and the vomiting center. They have a rapid onset of action and can be given as a single dose before chemotherapy. Ondansetron and granisetron, in particular,...
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists01:29

Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists

Dopamine receptor antagonists, also known as antipsychotic agents, are critical in managing chemotherapy-induced vomiting. These antiemetic agents block dopamine receptors in the chemoreceptor trigger zone (CTZ), inhibiting signal transmission to the vomiting center. Antipsychotic agents encompass phenothiazines (PTZ), butyrophenones, benzamides, and thienobenzodiazepines (Zyprexa), which are utilized for their antiemetic and sedative properties.
Phenothiazines, such as prochlorperazine...
Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...

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Related Experiment Video

Updated: Jul 10, 2026

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
08:25

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System

Published on: April 11, 2018

[Prescription errors in chemotherapy].

M S Díaz-Carrasco1, A Pareja, A Yachachi

  • 1Servicio de Famacia Hospitalaria, Hospital Universitario Virgen de la Arrixaca, Murcia. msacramento.diaz@carm.es

Farmacia Hospitalaria : Organo Oficial De Expresion Cientifica De La Sociedad Espanola De Farmacia Hospitalaria
|October 19, 2007
PubMed
Summary

Pharmacy departments play a crucial role in detecting medication errors in chemotherapy prescriptions. Pharmaceutical validation significantly enhances patient safety by identifying and resolving potential adverse drug events before dispensing.

Related Experiment Videos

Last Updated: Jul 10, 2026

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
08:25

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System

Published on: April 11, 2018

Area of Science:

  • Oncology Pharmacy
  • Medication Safety
  • Pharmaceutical Sciences

Context:

  • Chemotherapy prescriptions are complex and prone to errors.
  • The pharmacy department's role in error detection is critical for patient safety.
  • A retrospective analysis of medication errors in cytostatic drug prescriptions was conducted.

Purpose:

  • To analyze the role of pharmacy departments in identifying prescription errors for cytostatic drugs.
  • To classify and quantify medication errors in chemotherapy preparation.
  • To assess the potential impact of these errors on patient treatment.

Summary:

  • A two-year retrospective study identified 135 medication errors in 43,188 parenteral cytostatic drug preparations.
  • The most common errors included incorrect dosage (38.5%) and drug omission (21.5%).
  • All detected errors were classified as potentially serious (Level B) as they were intercepted before dispensing, with 66 potential adverse drug events identified.

Impact:

  • Pharmaceutical validation of chemotherapy prescriptions is essential for improving patient safety.
  • Early detection of errors, such as dose reductions and omissions, can prevent reduced treatment efficacy.
  • The findings underscore the indispensable role of pharmacists in the safe administration of cancer therapies.