Myosin Va controls oligodendrocyte morphogenesis and myelination

Jacob A Sloane1, Timothy K Vartanian

  • 1Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Institutes of Medicine, Boston, Massachusetts 02215, USA.

Summary

Myosin Va is essential for proper oligodendrocyte development and myelination. Loss of myosin Va function impairs brain myelination and affects oligodendrocyte structure, impacting neurological function in Griscelli's syndrome type 1.

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