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Postural control in patients with Down syndrome.

Manuela Galli1, Chiara Rigoldi, Luca Mainardi

  • 1Dipartimento di Bioingegneria, Politecnico di Milano, Milano, Italy. galli@biomed.polimi.it

Disability and Rehabilitation
|October 19, 2007
PubMed
Summary

Individuals with Down syndrome exhibit unstable postural control, with increased oscillations detected through force platform analysis. These findings highlight potential balance deficits contributing to functional challenges in this population.

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Area of Science:

  • Neuroscience
  • Human Physiology
  • Biomedical Engineering

Background:

  • Down syndrome is a genetic disorder associated with various developmental challenges.
  • Postural control is crucial for maintaining balance and executing daily activities.
  • Individuals with Down syndrome often experience difficulties with motor skills and balance.

Purpose of the Study:

  • To evaluate and quantify postural control in young adults with Down syndrome.
  • To compare the postural control of individuals with Down syndrome to a non-handicapped control group.
  • To identify specific characteristics of postural instability in Down syndrome.

Main Methods:

  • Sixty young adults with Down syndrome and 10 non-handicapped controls participated.
  • Postural control was assessed using a force platform for 30-second trials.

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Last Updated: Jul 10, 2026

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  • Data were analyzed in both time and frequency domains under eyes-open and eyes-closed conditions.

    • Main Results:

    • Subjects with Down syndrome demonstrated significantly unstable postural control compared to controls.
    • Frequency domain analysis revealed increased oscillations in both anterior-posterior and medio-lateral directions for the Down syndrome group.
    • Time domain analysis confirmed increased medio-lateral oscillations, while no significant difference was observed between eyes-open and eyes-closed conditions for those with Down syndrome.

    Conclusions:

    • Individuals with Down syndrome possess a deficient postural control system.
    • These postural deficits may partially explain common functional balance problems observed in Down syndrome.
    • Further research into targeted interventions for postural control in Down syndrome is warranted.