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Updated: Jul 10, 2026

Generation of Multicellular Human Primary Endometrial Organoids
Published on: October 4, 2019
Morphological changes in endometrium of hemodialyzed women of reproductive age
Katarzyna Skórzewska1, Stanisław Radowicki, Joanna Matuszkiewicz-Rowinska
1Department of Gynecological Endocrinology, Medical University Warsaw, Warsaw, Poland. kskorzewska@gmail.com
Aim:
The aim of the study was to evaluate endometrial morphology and its correlation with hormonal profile in uremic women of reproductive age undergoing hemodialysis.
Materials And Methods:
Sixty-three hemodialyzed women aged 18-45 years were enrolled into the study, 38 of whom gave their informed consent to undergo endometrial aspiration biopsy and measurement of hormonal profile.
Results:
Abnormal endometrial morphology was noted in 79% of the hemodialyzed women. Atrophic endometrium was observed in almost all uremic patients with secondary amenorrhea. Endometrial biopsy revealed one case of adenocarcinoma in situ. Analysis of the relationship between hormonal profile and endometrial morphology revealed the substantial influence of estradiol on endometrium.
Conclusions:
Abnormal endometrial changes are often noted in uremic women of reproductive age undergoing hemodialysis. Endometrial biopsy should be carried out as a safe and convenient procedure for the detection of pathological changes in uremic women.
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