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Related Experiment Videos

Oropharyngeal colonization in the elderly.

S Sveinbjörnsdóttir1, S Gudmundsson, H Briem

  • 1Department of Internal Medicine, Borgarspitalinn (Reykjavik City Hospital), Iceland.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|November 1, 1991
PubMed
Summary

Gram-negative bacillary colonization is more common in hospitalized elderly individuals. This oropharyngeal colonization is transient and may not be a significant risk factor for pneumonia in this population.

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Area of Science:

  • Geriatric Medicine
  • Infectious Diseases
  • Microbiology

Background:

  • Oropharyngeal colonization by gram-negative bacilli is a concern in the elderly.
  • Understanding colonization prevalence across different living situations is crucial for geriatric care.

Purpose of the Study:

  • To determine the prevalence of gram-negative bacillary oropharyngeal colonization in geriatric populations.
  • To investigate the incidence and patterns of colonization in hospitalized elderly patients.
  • To assess the association between oropharyngeal colonization and lower respiratory tract infections.

Main Methods:

  • Cross-sectional study comparing healthy, nursing facility, and hospitalized elderly groups.
  • Longitudinal study with serial weekly cultures in hospitalized elderly patients.

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  • Oropharyngeal cultures used to identify gram-negative bacilli.
  • Main Results:

    • Hospitalized elderly had significantly higher colonization rates (23%) compared to community-dwelling (7-10%) or nursing facility residents (7-10%).
    • Colonization in hospitalized patients was intermittent and decreased over time.
    • Hospitalization and prior antimicrobial treatment were associated with increased colonization.

    Conclusions:

    • Gram-negative bacillary oropharyngeal colonization is more prevalent in hospitalized elderly individuals.
    • Colonization is transient and its role as a pneumonia risk factor in the elderly appears limited.