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Related Experiment Videos

Antibiotics for incomplete abortion.

W May1, A M Gülmezoglu, K Ba-Thike

  • 1Keck School of Medecine, University of Southern California, USC Division of Medical Education, 1975 Zonal Avenue KAM 218 B, Los Angeles, California 90033, USA. winmay@usc.edu

The Cochrane Database of Systematic Reviews
|October 19, 2007
PubMed
Summary
This summary is machine-generated.

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Routine antibiotic prophylaxis for incomplete abortion did not show a difference in infection rates. More research is needed to determine the effectiveness of antibiotics in preventing complications from incomplete abortions.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Disease Prevention
  • Reproductive Health

Background:

  • Unsafe abortions lead to significant healthcare costs and long-term reproductive complications.
  • Antibiotic prophylaxis may prevent adverse outcomes following surgical evacuation for incomplete abortion.
  • Current clinical practice regarding routine antibiotic use is inconsistent.

Purpose of the Study:

  • To evaluate the effectiveness of routine antibiotic prophylaxis in women undergoing surgical evacuation for incomplete abortion.
  • To determine if routine antibiotics reduce post-procedural complications.

Main Methods:

  • Systematic review of randomized controlled trials.
  • Searched major databases including Cochrane Controlled Trials Register, PubMed/MEDLINE, EMBASE, and Popline up to January 2007.

Related Experiment Videos

  • Included trials comparing routine antibiotic prophylaxis versus no routine prophylaxis.

    • Main Results:

    • One study with 140 women was included; a second trial was excluded due to high loss to follow-up.
    • No significant difference in postabortal infection rates was observed between the routine prophylaxis and control groups.
    • Low compliance with antibiotic treatment was noted in the included study.

    Conclusions:

    • Insufficient evidence exists to support or refute the routine use of antibiotic prophylaxis for women with incomplete abortion.
    • Further high-quality randomized controlled trials are needed to clarify the role of antibiotic prophylaxis in this setting.