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Family interventions for bipolar disorder.

L P Justo1, B G O Soares, H M Calil

  • 1Universidade Federal de Sao Paulo, Departmento de Psicobiologia, Rua Napoleao de Barros 925, Vila Clementino, Sao Paulo, Brazil, CEP 04024002. luisjusto1@ig.com.br

The Cochrane Database of Systematic Reviews
|October 19, 2007
PubMed
Summary
This summary is machine-generated.

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Current evidence on family interventions for bipolar disorder is limited and inconsistent. More high-quality randomized controlled trials are needed to determine if these approaches offer significant benefits as an adjunctive treatment.

Area of Science:

  • Psychiatry and Mental Health
  • Clinical Psychology

Background:

  • Pharmacological treatments are the primary intervention for bipolar disorder but are often insufficient alone.
  • Adjunctive psychosocial interventions, particularly family interventions, may improve patient outcomes and illness course.
  • Family interventions can alleviate the burden on caregivers, facilitating patient support.

Purpose of the Study:

  • To review the effectiveness of family interventions in bipolar disorder treatment.
  • To compare family interventions against no intervention and other intervention types.

Main Methods:

  • Searched multiple electronic databases (CCDANRCT-Studies, CCDANCTR-References, CENTRAL, MEDLINE, EMBASE, LILACS) and reference lists.
  • Included randomized controlled trials (RCTs) and quasi-randomised trials involving individuals with bipolar disorder and their families.

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  • Assessed primary outcomes such as symptom status and relapse rates.

    • Main Results:

    • Seven RCTs with 393 participants were included; all used psychoeducational methods, one included systems psychotherapy.
    • All participants received pharmacotherapy; meta-analysis was not possible due to study heterogeneity.
    • Five studies comparing family interventions to no intervention showed no significant added effect; three studies comparing different family interventions had inconsistent findings.

    Conclusions:

    • The evidence base for family-oriented approaches in bipolar disorder is small and heterogeneous.
    • Definitive conclusions on the efficacy of family interventions as adjunctive treatment cannot yet be drawn.
    • Further well-designed RCTs are a research priority to establish the effectiveness of these interventions.