Related Experiment Video
Updated: Jul 10, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
Published on: July 28, 2020
[Neoadjuvant and adjuvant therapies for solid tumours]
Volker Heinemann1, Nicolas Moosmann
1Medizinische Klinik und Poliklinik III, Klinikum Grosshadern LMU München. Volker.Heinemann@med.uni-muenchen.de
Abstract:
Today adjuvant or neoadjuvant therapies are standard treatment for many types of cancer. Chemotherapy, radiotherapy, hormone therapy or immunotherapy applied before, during or after an operation can lower the risk of relapse and hence, increase the chances of a cure. After neoadjuvant therapy, frequently the organ does not have to be removed in the subsequent operation. Depending on the risk of relapse, adjuvant therapies are employed after due consideration of benefit, risk and duration of treatment. In ongoing clinical studies, the possibilities of influencing the effect of epidermal growth factor (EGF) as well as vascular endothelial growth factor (VEGF) are being investigated.
Related Concept Videos
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Tumor Immunotherapy
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Treatment Resistent Cancers
