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Published on: April 19, 2022
Endoscopic hemostasis by using the TriClip for peptic ulcer hemorrhage: a pilot study
Chun-Yiu Oliver Chan1, Kwok-Kay Kevin Yau, Wing-Tai Siu
1Hong Kong, China.
Gastrointestinal Endoscopy
|October 20, 2007
Summary
The TriClip device shows feasibility for initial control of peptic ulcer hemorrhage. However, this pilot study did not demonstrate clear advantages over existing methods for arresting bleeding vessels.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Medical Device Technology
Background:
- Peptic ulcer hemorrhage management lacks extensive literature on the TriClip device's feasibility, efficacy, and safety.
- A pilot study was essential to evaluate the TriClip endoscopic clipping device for controlling peptic ulcer bleeding.
Purpose of the Study:
- To assess the feasibility, efficacy, and safety of the TriClip endoscopic clipping device in managing peptic ulcer hemorrhage.
- To determine the initial hemostasis rate, recurrent bleeding rate, and ulcer healing after TriClip application.
Main Methods:
- Prospective evaluation of 27 patients (Forrest type I and IIa peptic ulcer hemorrhages) at a regional government hospital.
- TriClips were used for initial hemostasis, with salvage procedures if needed. Endoscopy at 24 hours and 8 weeks assessed safety, recurrence, and healing.
Main Results:
- Successful initial hemostasis with TriClips alone was achieved in 81.5% (22/27) of cases.
- Recurrent bleeding occurred in 14.8% (4/27), with TriClips dislodged in 40.7%. Permanent hemostasis rate was 67%.
- No morbidity or mortality was observed, and all ulcers healed within 8 weeks.
Conclusions:
- The TriClip device is feasible for the initial management of peptic ulcer hemorrhage.
- This pilot study did not identify significant advantages of the TriClip over other methods for controlling bleeding vessels.
- Further comparative studies are needed to establish the definitive role of the TriClip.
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