Natural history and etiology of high pressure voiding in male infants
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Updated: Jul 10, 2026

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
Published on: August 14, 2019
Midori Ichino1, Yasuhiko Igawa, Satoshi Seki
1Department of Urology, Shinshu University School of Medicine, Matsumoto, Japan.
Insights
High voiding pressure in infants stems from detrusor-sphincter dyscoordination and hypercontractility. Maturation improves this condition primarily through reduced detrusor hypercontractility.
Area of Science:
- Pediatric Urology
- Urodynamics
- Infant Lower Urinary Tract Function
Background:
- High voiding pressure in male infants is a clinical concern.
- Understanding its etiology and maturation patterns is crucial for diagnosis and management.
Purpose of the Study:
- Determine the causes of high voiding pressure in male infants.
- Clarify the mechanisms behind its improvement with age.
Main Methods:
- Retrospective review of 106 videourodynamic studies from 78 male infants.
- Analysis of age, bladder capacity, and maximum voiding detrusor pressure.
- Continuous fluoroscopic recording of lower urinary tract during 64 voiding phases.
Main Results:
- Maximum voiding detrusor pressure negatively correlated with age and bladder capacity.
- Observed increased detrusor pressure, sphincter activity, and urethral abnormalities.
- Urine stream interruption occurred in 92% of patients, independent of age.
Conclusions:
- High voiding pressure results from detrusor-sphincter dyscoordination and hypercontractility.
- Maturation improves this condition mainly via resolution of detrusor hypercontractility.
- External sphincter relaxation was adequate in all cases.
Purpose:
We sought to determine the etiology of high pressure voiding in male infants, and to clarify the mechanisms of its improvement with maturation.
Materials And Methods:
We retrospectively reviewed 106 videourodynamic studies obtained from 78 male infants with either congenital renal abnormalities or episodes of urinary tract infection, without any neurological disorders or lower urinary tract symptoms. We evaluated the relationship between age, bladder capacity and maximum voiding detrusor pressure. To evaluate voiding patterns more precisely fluoroscopic images of the lower urinary tract were continuously recorded in 64 voiding phases.
Results:
Maximum voiding detrusor pressure showed a significant negative correlation with age as well as bladder capacity. Sharply increased detrusor pressure was noted, as were increased sphincter electromyographic activity, dilated posterior urethra and interruption of urinary stream associated with intermittent closure of the membranous urethra. Sufficient relaxation of the external sphincter was observed in all cases. True maximum voiding detrusor pressure also exhibited a significant negative correlation with age. Interruption of urine stream was commonly observed (92% of patients). Neither mean number nor duration of urine stream interruptions changed with age. The increase in detrusor pressure in response to sphincter contractions revealed a significant negative correlation with age.
Conclusions:
High voiding pressure in male infants results from detrusor-sphincter dyscoordination and detrusor hypercontractility in response to the dyscoordination. Its improvement with maturation is mainly due to resolution of detrusor hypercontractility.
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