Related Experiment Video
Updated: Jul 10, 2026

Tuina Intervention in Sodium Monoiodoacetate Injection-Induced Rat Model of Knee Osteoarthritis
Published on: January 12, 2024
Localized pigmented villonodular synovitis in the knee associated with locking symptoms
Tadahiko Yotsumoto1, Jyunji Iwasa, Yuji Uchio
1Department of Orthopaedics, Shimane University School of Medicine, 89-1 Enya-cho, Izumo-shi, Shimane 693-8501, Japan. sssyotsu@yahoo.co.jp
Abstract:
Pigmented villonodular synovitis (PVNS) occurs in the knee more frequently than other joints. Most cases involve diffuse PVNS while the localized type is relatively rare. This report describes a patient who had PVNS and a lateral meniscus injury which induced locking symptoms in the knee. A closed reduction of the meniscus tear was performed under local anesthesia. However, complete extension of the knee was not achieved and the locking symptoms persisted. MRI examination showed a neoplastic lesion measuring approximately 2 x 2 cm in the intercondylar space together with a lateral meniscus tear. The lesion was resected using arthroscopy. Histology of the resected lesion demonstrated localized PVNS. There has not been any recurrence of locking symptoms or PVNS two years after surgery. The findings in this case suggest that localized PVNS may contribute to locking symptoms in a patient with meniscal pathology.
Related Concept Videos
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...
Ankle Joint
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...